The global collagen skin matrix market size was worth around USD 587.9 million in 2024 and is predicted to grow to around USD 1090.5 million by 2035 with a compound annual growth rate (CAGR) of 5.78% from 2025 to 2035. An increasing significance of skincare, innovative formulations & delivery mechanisms, along with preference towards preventive healthcare, are driving the collagen skin matrix market globally.